понедељак, 11. фебруар 2019.

Nature antibiotics

Origano oil


Its use for chickens was mentioned above and in the laboratory, it has also been studied in mice.
Helicobacter pylori (H. pylori) causes stomach infections in two-thirds of humans worldwide (3). The side effects include peptic ulcers and even stomach cancer.
Published in 2016, researchers fed mice a 2:1 mixture of essential oils made from summer savory (Satureja hortensis) and oregano (Origanum vulgare) (4).
The results? In 70% of mice, this mixture was said to eradicate the pathogens. Given that H. pylori has many antibiotic resistant strains, they suggested:
“…this essential oil mixture has great potential as a new, effective, and safe therapeutic agent against H. pylori.”
Another study, this one being in vitro, tested oregano essential oil against 59 different bacterial strains. It was said to demonstrate varying degrees of effectiveness against all. The researchers claimed it “completely inhibits the growth of multidrug-resistant cystic fibrosis pathogens” which were tested in the experiment (5).

Oil Of Oregano 
Oil of oregano takes care of pathogenic bacteria without disrupting beneficial bacteria. It is also antiviral and antifungal which makes it a powerful, natural antibiotic with a three-in-one combination that rivals pharmaceuticals while not encouraging antibiotic resistance.

The key antimicrobial ingredient in oil of oregano is carvacrol. You should ensure that your source is at least 70 percent carvacrol content in order to be effective.

Garlic


Cultures across the world have long recognized garlic for its preventive and curative powers.
Research has found that garlic can be an effective treatment against many forms of bacteria, including Salmonella and Escherichia coli (E. coli). Garlic has even been considered for use against multi-drug resistant tuberculosis.

 

Garlic

Up first is the natural antibiotic garlic! Garlic has been used medicinally by cultures around the world for thousands of years. In fact, it was used in the 1700s to ward off the plague.

Garlic possesses potent antibiotic, antiviral, antifungal, and antimicrobial properties and is able to help protect and facilitate removal of unfriendly bacteria. It is also very high in natural antioxidants that destroy free radicals, which also supports a strong immune system.

The active ingredient in garlic, allicin, is the key component to killing and warding off harmful bacteria. Crush it to activate these compounds, and eat it raw, in a warm tea or in lightly cooked food.

Ancient onion and garlic medicinal recipe cures drug-resistant superbug infections



by: Amy Goodrich
October 14, 2015
A thousand-year-old potion found in an Old English manuscript in the British Library to treat an eye infection has amazed the scientific world. Researcher at the University of Nottingham found it to be very effective against methicillin-resistant Staphylococcus aureus, known as MRSA.
Combating MRSA and other antibiotic-resistant bacteria is one of the biggest challenges hospitals face each year. Due to overuse of and overexposure to antibiotics, some bacterial strains have evolved to withstand our drugs. This gives rise to a whole army of superbugs which are very hard to treat and cause the death of at least 23,000 people each year.
Anglo-Saxon expert Dr. Christina Lee, from the University of Nottingham, found and translated this “eye salve” from Bald’s Leechbook, which is a collection of ancient remedies to treat a wide range of ailments.
Take cropleek and garlic, of both equal quantities, pound them well together, take wine and bullocks’ gall, of both equal quantities, mix with the leek, put this then into a brazen vessel, let it stand nine days in the brass vessel, wring out through a cloth and clear it well, put it into a horn, and about night time apply it with a feather to the eye; the best leechdom. — Recipe to treat a stye, translated from Bald’s Leechbook.
Only after teaming up with colleague Dr. Freya Harrison and her team from the microbiology department were they able to recreate the ancient salve.
They tried to make the remedy as close as possible to the original recipe, which was not easy since our crops now differ a lot from the ones in the 10th century.
They tested the eye salve on a large culture of MRSA, and the results were rather unexpected.
“We did not see this coming at all,” said microbiologist Harrison, the lead researcher. “We thought that Bald’s eye salve might show a small amount of antibiotic activity. … But we were absolutely blown away by just how effective the combination of ingredients was,” she added.
They found that the unique combination of Bald’s eye salve killed up to 90 percent of MRSA. To back up their findings, Texas Tech University tested the salve on MRSA skin wounds on mice and came to the same conclusion.
The salve might be more powerful than any antibiotic on the market right now.
“We let our artificial ‘infections’ grow into dense, mature populations called ‘biofilms,’ where the individual cells bunch together and make a sticky coating that makes it hard for antibiotics to reach them,” Harrison said in a statement. “But unlike many modern antibiotics, Bald’s eye salve has the power to breach these defenses.”
This new study shows us that we can learn important lessons from our past. It is actually not the first time researchers found the answer in nature instead of the lab. There may be a lot of dodgy medieval practices and remedies out there, but great wisdom is hiding in these ancient books as well. Artemisinin to treat malaria, for instance, is another substance that came to us via an age-old Chinese medical text.
“This truly cross-disciplinary project explores a new approach to modern health care problems by testing whether medieval remedies contain ingredients which kill bacteria or interfere with their ability to cause infection,” Dr. Harrison concluded.
This research project will be presented at the Society for General Microbiology conference in Birmingham, UK, and the results will also be submitted to the journal Nature.
Sources for this article include:
http://www.bbc.com
http://gizmodo.com
http://www.usatoday.com
http://www.newscientist.com
http://www.cdc.gov
http://www.sciencealert.com
http://www.nottingham.ac.uk

 

Honey

Since the time of Aristotle, honey has been used as an ointment that helps wounds to heal and prevents or draws out infection.
Healthcare professionals today have found it helpful in treating chronic wounds, burns, ulcers, bedsores, and skin grafts. For example, results of a study from 2016 demonstrate that honey dressings can help to heal wounds.
The antibacterial effects of honey are usually attributed to its hydrogen peroxide content. However, manuka honey fights off bacteria, though it has a lower hydrogen peroxide content.
A 2011 study reported that the best-known type of honey inhibits approximately 60 kinds of bacteria. It also suggests that honey successfully treats wounds infected with methicillin-resistant Staphylococcus aureus (MRSA).
Antibacterial properties aside, honey may help wounds to heal by providing a protective coating that fosters a moist environment.
Honey is one the oldest known antibiotics, tracing back to ancient times. Egyptians frequently used honey as a natural antibiotic and skin protectant.
Honey contains hydrogen peroxide, which may account for some of its antibacterial properties. It also has a high sugar content, which can help stop the growth of certain bacteria.
Additionally, honey has a low pH level. This works to pull moisture away from bacteria, causing the bacteria to get dehydrated and die off.
To use honey as an antibiotic, apply it directly to the wound or infected area. The honey can help kill off the bacteria and aid in the healing process. If possible, opt for raw Manuka honey. This form of honey offers the most health benefits. You can purchase raw Manuka honey here.
You can also ingest honey to aid in the treatment of internal infections. Simply swallow a whole tablespoon or stir it into a warm cup of herbal tea for a soothing treat.
Honey is generally safe to use on the skin or in the body, though you should never give honey to an infant under 1 years old. Instead, consult your doctor for an appropriate alternative.


Perhaps the most palatable antibiotic comes in the form of manuka honey. Applied topically, it can kill a wide range of pathogens including MRSA and flesh-eating bacteria. It was also found that the treated bacteria did not build up any resistance, which would eventually render manuka honey ineffective.

This is certainly not an exhaustive list of natural antibiotics, but a great start for an all natural pharmacy. Also, consider reishi, pau d'arco, Una de Gato, olive leaf extract, cloves, turmeric and even lemons to round out your antibiotic arsenal.

Manuka honey

Last but not least, we circle back to this unique form of honey. As mentioned, the idea of using it for kennel cough in dogs and other veterinarian purposes had been proposed. What research is there to suggest that might work?
Actually, a fair amount.
There are over 200 research entries on PubMed about using Manuka honey for gingivitis, periodontal disease (43), dental plaque (44), neuropathic diabetic foot ulcers (45), sinus infections (46), and even MRSA (47), among others. Generally, they’re looking at it for topical uses.
During that segment on the Dr. Oz show about powerful natural antibiotics, the first one they talked about was using Manuka honey for cuts and scrapes. Oz closed the discussion by saying “this stuff is not just science fiction, it really does work.”
Having covered other pets, we can’t forget about alternative antibiotics for horses!
There was actually a clinical trial done involving eight adult horses and whether this honey would help with the healing of contaminated wounds (48). The results were mixed though. Even though the Manuka treatment group experienced a smaller wound area by reducing retraction, it did not change the overall healing time for those horses.
Going back to humans, a randomized study involving 108 patients with sloughy venous leg ulcers seemed to show a lot of promise (49).
After 4 weeks, MRSA was eradicated from 70% of the patients (7 total) treated with Manuka honey, compared to 16% (1 total) given hydrogel wound treatments.
There has been a lot of controversy about whether honey is better or the same for dental health versus refined sugar. A couple of years ago, a clinical study was done involving 30 children with a history of tooth infection or decay (50):
  • From 9 to 12 years old.
  • All had at least one decayed tooth.
  • 15 of the kids were given Manuka honey to use twice daily.
  • 15 of the kids did not get it. They were used as a control group.
The results? After being measured on day 10 and 21:
Children using Manuka honey showed statistically significant reductions in salivary S. mutans”

Manuka flower, photo credit: Forest & Kim Starr
Salivary Streptococci mutans are believed to contribute to cavities, tooth decay, and gum infection. For reducing colony counts, the researchers said Manuka might be an “effective adjunctive oral hygiene measure.”
Some herbal remedy websites claim that manuka honey heals cavities, but that is flat out wrong. Nothing can repair a tooth cavity, other than your dentist with a drill and filling.
While the honey’s purported medicinal uses come from topical and oral application, it is a delicacy which is quite in demand as a food.
People love the taste since it’s like regular honey, only stronger. Its unique flavor is because the bees make it using Manuka flower nectar, a flowering tree which is only native to New Zealand.
It’s not cheap and it’s hard to find in stores, but it’s definitely worth trying this tasty sweetener.

 

Echinacea

 Echinacea has been used to treat infections for many years.

Native American and other traditional healers have used echinacea for hundreds of years to treat infections and wounds. Researchers are beginning to understand why.
A study published in the Journal of Biomedicine and Biotechnology reports that extract of Echinacea purpurea can kill many different kinds of bacteria, including Streptococcus pyogenes (S. pyogenes).
S. pyogenes is responsible for strep throat, toxic shock syndrome, and the "flesh-eating disease" known as necrotizing fasciitis.
Echinacea may also fight inflammation associated with bacterial infection. It is available to purchase in health stores or online.
Echinacea has been used to treat a wide variety of infections for hundreds of years. Traditionally, it was used to treat open wounds, diphtheria, blood poisoning, and other bacterial related illnesses.
Today, this potent herb is used mostly for colds and flu, due to its ability to destroy the most dangerous forms of bacteria such as staphylococcus aureus, which causes deadly MRSA.

What should you take for a cold? You often hear people say that Echinacea is a good herbal remedy to relieve the symptoms.
Since the common cold is a viral infection, antibiotics have no effect on it. What’s interesting about Echinacea is there have been studies suggesting it might be antibacterial and be a natural antiviral (16) (17).
Echinacea, which is actually a type of daisy, is one of the most extensively studied herbs. PubMed shows over a thousand entries for it and if you filter those to just clinical trials, you get 83.
Regarding its potential as a natural antiviral supplement, the most interesting clinical trial is from 2012 simply due to the sheer size of it.
The goal was to see if it might help with cold prevention. Conducted by Cardiff University, 755 healthy people were given an Echinacea supplement or a placebo to take for a 4 month period. The researchers claimed:
Echinacea reduced the total number of cold episodes, cumulated episode days within the group, and pain-killer medicated episodes.”
The difference was said to be a 26% shorter duration of illness. Recurrent colds were cut by 59% in the study. While it sounds great, the UK government’s NHS pointed out some major concerns they had about the study (18):
  • No results table was published
  • No estimates of error around measures of effect were reported
  • No declaration of funding
  • Only partial disclosure for conflicts of interest
  • Selective reporting of results
Do natural antibiotics work? While technically this study was looking at antiviral, the concerns expressed above are reasons why you have to really look past the headlines regardless of what a purported herbal cure or treatment may be. Even though it’s well studied, Echinacea remains unproven.


Karanfilić

Clove

Clove has traditionally been used in dental procedures. Research is now finding that clove water extract may be effective against many different kinds of bacteria, including E. coli.
Koloidno srebro

Colloidal silver has been known as an effective antibiotic for centuries. In the early 1900s, Alfred Searle, founder of the Searle pharmaceutical company, discovered that it could kill the most deadly pathogens. 
Searle stated that applying colloidal silver to human subjects has been done in a large number of cases with astonishing results. The main advantage was that it was rapidly fatal to microbes without toxic action on its host.

Recent research has also stated that colloidal silver can destroy antibiotic resistant microbes like MRSA, the bird flu, and SARS.

Colloidal silver

So far everything discussed is a spice or a derivative of one. There are also minerals which have shown some promise in preliminary research. Perhaps the most talked about is silver.
What is colloidal silver? It is the suspension of microscopic silver particles in distilled water, which is created using electrolysis. It is sold as a dietary supplement.
The bar on the left (group 1) was treated with saline, while the other 4 bars were treated with topical colloidal silver solution in dosages ranging from as high as 30 ppm (group 2) to as low as 5 ppm (group 5).
A recent study involving sheep found that when compared to the control groups (non-treated), the groups given a topical colloidal silver solution “showed a significant decrease in biofilm biomass” from Staphylococcus aureus (11).
Even though they said that the study’s model “appears safe” it’s important to reiterate that this is unproven and may even have harmful side effects in humans. The FDA put out a consumer warning several years ago that silver dietary supplements might cause permanent skin discoloration (12).
Nearly a decade ago, there was an interesting report in a medical journal of using it colloidal silver on a 12 year old child with severe cystic fibrosis, but it is not approved for that nor any other medical use (13). A lot more research needs to be done on this mineral before it could even be considered as a candidate for treatment.

Mustard oil

Mustard oil

Oregano isn’t the only one on this list. Mustard seed essential oil also appears to work.
Because of a compound called allyl isothiocyanate, one in vitro study said it was “the most effective” when compared to oregano and thyme oils, which were all tested against foodborne pathogens (salmonella, staph, and listeria) (6).
In 2016, a discussion among doctors and scientists on respiratory infections took place in Frankfurt, Germany. This “expert panel” recommended the consideration of mustard oils as a possible future therapy (7).
The article summarizing the meeting, which was published in a medical journal, purported that “efficacy and safety of mustard oils had been confirmed for adults and children by several clinical studies.” [eg. B. Fintelmann V et al. Curr Med Res Opin 2012; 28: 1799-807; Goos KH et al. Drug Res 2006; 56: 249-57; Goos KH et al. Drug Res 2007; 57: 238-46]
Professor Ludger Klimek of Wiesbaden, Germany was quoted as saying:
Especially in the early stages of inflammatory respiratory disorders, include herbal medicines for the treatment of first choice because, unlike synthetic chemical antibiotics, mustard oils have not only a single mechanism of action, but they act multimodal.”
It will be exciting to see in the future whether others will agree or not, after further research is done.

Cimet

Cinnamon

A search for the two words “cinnamon antibiotic” on PubMed yields over 100 results. Not only has it been studied extensively for having antibacterial properties on its own, but it has even been looked at for possibly combining with traditional antibiotics like doxycycline (8).
On its own, doxycycline is a type of tetracycline antibiotic commonly used for cystic acne, urinary tract infections, gum disease, and many others.
Cinnamon bark essential oil has been tested in lab experiments for things ranging from drug-resistant E. coli strains to possible benefits against Listeria on meat (9) (10).
Whether we will ever see this spice developed into actual treatments may be complicated by the fact that the most popular type, cassia cinnamon, is toxic to the human liver. Instead, perhaps the Ceylon variety might offer more potential for cinnamon benefits in healthcare.
Coconut oil

Coconut oil

This is one of the most overhyped superfoods. Many of its purported benefits are exaggerated or outright fabricated, as is the case with the stretch mark coconut oil treatment.
That being said, there is scientific research to suggest that a type of saturated fat in it might have antibacterial and antifungal properties. That fat is lauric acid (C12:0).
The list of foods high in lauric acid is quite short. Aside from coconut, there’s palm nut oil, cinnamon oil, and goat milk. Regular milk from a cow has it too, but about half the amount versus goat. The plant-based sources of lauric acid have exponentially higher amounts – coconut oil is best at 48%.
One study wanted to see if lauric acid would work topically as a natural antibiotic for acne bacteria (31).
To be clear, not all pimples are caused by bacteria and in fact, the exact causes of this skin condition are poorly understood. But for some instances of inflammation, the bacterium Propionibacterium acnes (P. acnes) has been singled out as a likely culprit.
The study only involved mice and Petri dish experiments, so it’s hard to read too far into it. Mice don’t even have pimples, so they had to use the same type of bacteria and monitor the mice for ear swelling and abscesses, which were locations where they applied the P. acnes bacteria.
They found both lauric acid and another saturated fatty acid, decanoic acid (capric acid), seemed to work for acne bacteria. However, it was the lauric acid which was said to have strong antibiotic activity both in the mice as well as the Petri dish. Whether that translates to a natural cystic acne treatment though is untested.
A double-blind controlled human study looked at using coconut and olive oils for atopic dermatitis/eczema (32).
That type of dermatitis causes itchy skin which is often red, swollen, and sometimes cracked. Staphylococcus aureus bacteria will use this compromised skin as a breeding ground, which only further worsens the side effects.
After 26 patients received one or the other oil for a period of 4 weeks:
  • 5% (1 patient) who had topically applied the virgin coconut oil still tested positive for Staphylococcus aureus.
  • 50% (6 patients) of those applying olive oil still tested positive.
Those findings, along with “broad-spectrum activity” against the bacteria in lab experiments, led researchers to conclude it might be useful in natural topical antibiotics, as a proactive treatment against atopic dermatitis colonization.
While not a bacteria, drug-resistant Candida species are a growing problem. Fluconazole, sold under the brand name Diflucan, is one treatment used for this type of fungus. When coconut oil was pitted against it in an experiment, the researchers found the coconut performed better for some species, such as Candida krusei (33).
Who knows, perhaps future research using humans will find coconut oil derivatives are useful as a natural antifungal for candida, as well as antibacterial purposes. We will have to wait and see. It would be interesting to see researchers test it on nail fungus.

Grapefruit seed extract

Here’s one you don’t hear much about, nor is there a great deal of research on it. But what you can dig up on it is fascinating.
A University of Texas study pitted grapefruit seed extract against 5 commonly used topical antibacterial agents (34):
  • Bactroban
  • Nitrofurazone
  • Nystatin (mentioned above for denture stomatitis)
  • Silvadene
  • Sulfamylon
They tested these and the grape seed extract against 67 distinct biotypes in well plates. After being incubated overnight, they checked the plates and the extract was said to be “consistently antibacterial” against all and performed comparable to the proven topical ointments.
We’ve talked about a possible natural antibacterial for dogs, but how about bees? American foulbrood (AFB) is major problem for beehives. It can cause their destruction and the root of AFB is the spore forming Paenibacillus larvae.
A study concluded at least some forms of grapefruit seed extract could be used as a substitute for chemotherapeutic products, which are currently used for controlling the disease in beehives (35).
A small study involving 3 middle-aged men and 1 women took place in Nigeria. Each had a urinary tract infection (UTI) which tested positive for a different cause (36):
  • E. coli
  • Staphylococcus aureus
  • Pseudomonas aeruginosa
  • Klebsiella species
They were instructed to consume a dosage of 5 to 6 dried or fresh grapefruit seeds every 8 hours, for a period of 2 weeks.
All were said to respond favorably, with the exception of the man with P. aeruginosa. It was noted that his type of infection was antibiotic-resistant (gentamicin, tarivid, and augmentin failed). After using the grapefruit seed for 2 weeks, there was “reversal of the antibiotic resistance pattern.”
Obviously though, a lot more research needs to be done to find out if this may be a natural treatment for urinary tract infections, or any other type for that matter. You can’t say a non-controlled study of four people is evidence it can control bacterial infections!

Myrrh



When you hear of frankincense and myrrh, you probably think of the gifts the magi brought after the birth of baby Jesus. But that’s not the only time it’s mentioned in the Bible…
The Old Testament talks about camels who were loaded with balm and myrrh (Genesis 37:25). The Lord instructed Moses to use it as part of a sacred anointing oil (Exodus 30:23).
In the New Testament, Jesus was offered wine and myrrh before crucifixion (Mark 15:23) and then after, Nicodemus and Joseph of Arimathea brought it to wrap Jesus’ body (John 19:39):
Nicodemus also, who earlier had come to Jesus by night, came bringing a mixture of myrrh and aloes, about seventy-five pounds in weight.”
Clearly, this myrrh holds significance, but what is it exactly?
The Commiphora myrrha tree makes an aromatic resin, which is basically a natural gum. Also called African myrrh, it’s native to the Arabian peninsula and nearby countries in Africa, such as Ethiopia and Kenya.
At the open, we mentioned a lady claiming she used it in lieu of over the counter antibiotics for cats. Perhaps she is onto something, as there has been research in recent years suggesting it has antimicrobial activity.
In the lab, one compound in myrrh was found to have high activity against SA1199B, a strain of Staphylococcus aureus which is multidrug-resistant (37).
As far as myrrh essential oils, one study found them to have “moderate to high” activity against Gram-positive bacteria (38).
Another tested it against both Gram-positive and Gram-negative and found (39):
considerable inhibitory effects against all tested organisms, except Pseudomonas”
One scientific review proposed the possibility of using it as an ingredient in acne vulgaris products (40).
In terms of wound healing, a study involving mice found that (41):
Ointment formulations of both the oil and resin were found to be non-irritant at the concentrations used and showed significant increase in wound contraction rate, shorter epithelization time and higher skin breaking strength as compared to the negative control.”
They claimed the natural antifungal activity was comparable to the medication griseofulvin, while the antibacterial activity was comparable to ciprofloxacin.
A study which claimed to be “one of the most extensive on anti-virulence screenings” using 83 different essential oils claimed that myrrh – along with black pepper and cananga oils – demonstrate the most potential against Staphylococcus aureus (42). Perhaps in the future, compounds within these could be developed into new alternatives to antibiotics for some types of infections.


Reference:






This is The Most Powerful Natural Antibiotic Ever – Kills Any Infection In The Body


This is The Most Powerful Natural Antibiotic Ever – Kills Any Infection In The Body




Over the counter medicines are usually full of unnecessary chemicals, and often aren’t even that effective. This recipe for an all-natural tonic dates back hundreds of years and has proven to be effective for all that time.
This cleansing tonic is made form 100% natural ingredients and is known to kill gram-positive and gram-negative bacteria. It also has powerful anti fungal and antiviral properties and will increase blood flow to all parts of the body, and essential for all round great health.
 It has been known to cure many parasitic, fungal, viral and bacterial diseases and is a go to if you have feel you have an illness coming on, or just in times when you need a health boost.
Ingredients
  • 2 tbsp turmeric powder or 2 pieces of turmeric root
  • 24 oz/700 ml apple cider vinegar (organic)
  • 1/4 cup finely chopped garlic
  • 1/4 cup finely chopped onion
  • 2 fresh peppers-the hottest you can find (be careful when handling them)
  • 1/4 cup grated ginger
  • 2 tbsp grated horseradish
Directions
  1. Combine all the ingredients except the vinegar into a bowl
  2. Transfer the mix into a mason jar
  3. Pour some apple cider vinegar in to the top
  4. Close and shake well
  5. Keep the jar in a cool dry place for 2 weeks, shake well several times a day
  6. After 14 days squeeze well and strain the liquid through a strainer
  7. Use the rest of the dry mixture when cooking
Once you have finished this procedure, your tonic is ready to be consumed whenever you need it. It does not need to be refrigerated and should last a long time.
To take the tonic you should begin with 1 tablespoon a day, gargle and swallow the mixture. Be careful as the mixture is very hot and has a strong taste. You can eat a slice of lemon immediately after consuming to ease the burn.
Raise the amount until you are comfortable drinking 1 small glass per day to ward off disease and infection.